Cefic-lri Programme | European Chemical Industry Council

Projects

ECO47 – SNAPFISH: Searching for refiNed in vitro Approaches to Predict bioconcentration in FISH

Chemical regulations require information as to whether a chemical is bioaccumulative. Steady-state bioconcentration factors (BCFs) in fish reflect the net result of the various chemical uptake versus loss processes and can be determined directly.

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ECO50 – Incorporating spatial and seasonal variability in community sensitivity into chemical risk assessment (GETREAL)

GETREAL will provide this information on the variability in chemical sensitivity and explore its consequences for risk assessment.

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ECO49 – Microplastic Effect Thresholds for Aquatic Species (METAS)

Microplastics research has grown substantially over the past years due to concerns with the public, the scientific community and environmentalist groups. They are often detected in environmental compartments but the hazards and risks they pose are debated and largely unknown.

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ECO48 – NANO2PLAST: Extending nanoparticle models to open source models of the fate and transport of microplastic in aquatic systems

Plastic pollution has become a major environmental concern among the public and government agencies, and in recent years the presence of microplastics in aquatic and terrestrial systems worldwide has received increasing attention.

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ECO44 – A toxicokinetic mammalian modelling framework for bioaccumulation assessment

The general objective of this project is to build a toxicokinetic (TK) modelling framework for mammals and develop and integrate various data streams for mammalian B assessment. This research will expand the development, evaluation, and application of the CEFIC-LRI funded […]

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ECO42: Fate-directed toxicity testing and risk assessment of UVCBs

The objectives of this project are (1) to develop and test new approaches for fate-directed ecotoxicity assessment of UVCBs based on new combinations of analytical methods, dosing methods, fate directed fractionation, toxicity testing and models, (2) to conduct a case […]

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ECO45: Chemicals – Assessment of Risks to Ecosystem Services (CARES) II

This project aims to evaluate the practical applicability of an ecosystem services approach to prospective and retrospective chemical risk assessment.

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B18: Carcinogen Dose-Response Database for Threshold of Toxicological Concern (CDRD-TTC)

This project aims to generate a fully-curated, quality-controlled and publically-available database on genotoxic and non-genotoxic carcinogens. The novel database will form the basis of analysis of TTC distributions for cancer thresholds. The specific objectives of the research, in the context […]

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B17: SHINE: Target and non-target Screening of cHemicals in the Indoor enviroNment for human Exposure assessment

The last couple of years have seen substantial efforts expended on the development of sophisticated, high tier modelling of integrated exposure (including via indoor air), such as INTEGRA (developed in a CEFIC LRI project) and Merlin Expo; however these models […]

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ECO28: Modelling approaches for a scenario based assessment of chemically induced impacts on aquatic macroinvertebrate communities (MACROMOD)

The ecological risk assessment (ERA) of chemicals aims at quantifying the likelihood of adverse ecological effects posed on populations and the communities they comprise (sensu Forbes et al. 2011). Effects caused by the exposure of organisms to toxicants can however […]

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