Cefic-lri Programme | European Chemical Industry Council

Projects

B19.2 – Refinement of a framework for extrapolating of worker exposure measurement data

LRI B19.2 is an extension of Cefic-LRI B19 project: 'Extrapolating the Applicability of Worker Exposure Measurement Data'. The objective is to improve on the framework delivered in the previous B19 project, by 1) re-assessing the existing case studies in light […]

Read more

B15.3 – ECEL v3.0: Technical improvements and population of the integrated risk management measure (RMM) library

B15.3 is an extension of the “Cefic-LRI B15-2 project: Development of an integrated risk management measure library”. The main goal of this proposal is to upgrade ECEL v2.0 to ECEL v3.0 such that it is a well-designed, user-friendly tool with […]

Read more

B12.3 – Assessing the relevance of the dust contribution in consumer exposure to substances from consumer products and articles (DustEx extension)

Human exposure to semi-volatile organic compounds (SVOCs) present in materials is of great interest because of the large number of SVOCs used for different purposes in different materials; ranging from plasticizers in PVC to flame retardants in upholstery and clothing […]

Read more

B21 – In Vitro Data to Parameterise PBPK Models For Inhalation Exposure

This project aims at the generation and application of physiologically derived transport parameters in a PBPK model focusing on a more detailed description of substance uptake through the respiratory tract/via the inhalational route. This PBPK model is aimed to be […]

Read more

C7 – ELUMICA – Elucidating Microbial Metabolic Capacity

This project will carry out collaborative, mechanistically oriented research centered around the following three aims: Identify and quantify alterations in endogenous and xenobiotic-derived microbial metabolites; provide a basis to examine interspecies and interindividual differences in intestinal microbial metabolism; and develop […]

Read more

EMSG59 – Developing a quantitative AOP for liver-mediated thyroid modulation after prenatal exposure to a xenobiotic compound in the rat

This project aims at understanding the consequences of chemical-induced changes in liver physiology on thyroid hormone balance and related adverse health effects. The project will focus on prenatal exposure and development of the foetus and new-born in the rat as […]

Read more

ECO46 – Improved aquatic Testing and Assessment of cationic Polymers (iTAP)

The aim of this PROJECT PROPOSAL is to collate and update the existing global knowledge base on the available methods for the assessment of cationic polymers toxicity, fate properties as well as regarding their known descriptors used to develop Structure […]

Read more

C6 – Toxicogenomic Approaches to Support Read-Across

Read-across is an old concept that is being increasingly utilized in chemical risk assessment. The basic premise for read-across is that compounds with similar chemical structure will have the same biological activity either because they are metabolized to a common […]

Read more

C5 – XomeTox – evaluating multi-omics integration for assessing rodent thyroid toxicity

In combining an animal toxicity study with a multi-omics approach and advanced in silico methods for data interpretation, this project will contribute to “New research tools, such as […] genomics, present exciting approaches that have the potential to link information […]

Read more

C4 – Transcriptomics bioinformatics best practices in toxicogenomics for regulatory application

This project proposal aims to regroup toxicogenomics experts to test and further develop a regulatory ODAF (R-ODAF) proposal for the toxicogenomics community with the ambition to enable the regulatory bodies to consider omics as a relevant data type to support […]

Read more

Cefic-Lri Programme Responsible Care

Terms and Conditions of Use | Privacy Policy | Cookie Policy | Coockie Settings

© Copyright 2017 Cefic | European Chemical Industry Council. All rights reserved.