Intelligent testing
ECO59 : FRAGMENT-MNP: Developing a mechanistic model of Micro and NanoPlastic FRAGMentation in the ENvironmenT
The overarching objective of this project is to develop and deliver a pragmatic open-source mechanistic model of how environmental factors affect plastic fragmentation and degradation rates. The model will be applicable across a range of conditions in multiple environmental compartments. […]
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ECO58 : Comprehensive additive release and bioaccessibility model for risk assessment of micro- and nano-plastics in the environment
The ubiquitous occurrence of plastics in natural waters1, 2 is a consequence of vast and increasing utilization of synthetic polymers in commercial, industrial, and consumer applications. While the implications of continuous ecological exposure to plastic particles in the nano- to […]
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ECO57 : μPLANET – microPlastic Long-range transport Assessment aNd Estimation Tools
Recent research has highlighted the apparent ubiquity of plastic debris, including Microplastic Particles (MPs), across the planet and particularly in the oceans. The release of MPs to the environment represents a particular concern given their resistance to degradation. The continuous […]
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ECO56: UTOPIA: Development of a mUltimedia uniT world OPen-source model for mIcroplAstic
The main objective of UTOPIA is to develop an open-source unit world multimedia modeling platform to synthesize knowledge and understanding about the fate of microplastic in the environment. The UTOPIA project aims to deliver a general purpose open-source modeling platform […]
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ECO 55: Assessing the Impact of Sample Collection on Microbial Population and Validity Criteria in the OECD 309 Surface Water Mineralisation Test
This project will provide improved guidance on surface water sample collection, storage and treatment including a scientifically defensible maximum range between water source sampling and experimental temperature and a suite of quantitative and qualitative tests that further demonstrate inoculum viability […]
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ECO51 – SWiFT: Strengthening weight of evidence for FET data to replace acute fish toxicity
The use of fish embryo toxicity (FET) data for hazard assessments of chemicals, in place of acute fish toxicity (AFT) data, has long been the goal for many environmental scientists.
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B22 – TMEx-Complex: Tiered Methods for Quantifying Exposure to Complex Substances
Human exposure to chemicals is usually studied and understood in terms of the effect of a single pure chemical, but most humans are exposed to mixtures of chemicals. The project is focussed on determining how human exposure to chemicals is […]
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B18.2 – Incorporation of repeated dose study information for non-DNA-reactive carcinogens into the CPDB database and analysis of threshold values
This project is planned as extension of the project CEFIC LRI project B18, named “Database on Carcinogen Dose-response, including Information on DNA-reactivity, for TTC and beyond”, which is currently in its reporting phase. In this previous project, we updated the […]
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AIMT5.2 – A computational model for neural tube closure for in silico predictive toxicology of neural tube defects
The objective of this project is to translate the developmental ontology for neural tube closure, which was constructed in the LRI AIMT-5 project, into a computational model for predictive toxicology of neural tube defects. This represents a penultimate step for […]
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ECO43: Improving sediment toxicity testing design and data interpretation for very hydrophobic substances
The general objective of the proposed research is to improve sediment toxicity testing design, performance, and data interpretation for VHOCs and to develop guidance in order to maximize realism and value of future testing and thereby to support product and […]
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