Cefic-lri Programme | European Chemical Industry Council

Intelligent testing

ECO22-IRAS: Advancing the use of passive sampling in risk assessment and management of contaminated sediments: an inter-laboratory comparison study on measurements of freely dissolved (bioavailable) concentrations using different passive sampling formats

The main objective of this study is to map the state of the art in passive sampling sediments and to investigate which measures we can take to reduce any inter-method and -laboratory variation, in order to increase confidence in the […]

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EEM9.3-IC: Linking LRI AMBIT Chemoinformatic system with the IUCLID Substance database to Support Read-across of Substance endpoint data and Category formation

A major hurdle in using chemoinformatic systems is the lack of easily accessible data on substance identity including structures and composition e.g. constituents, impurities and additives as well as high quality, detailed endpoint data of chemical substances. This project is […]

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N4-WAG: Science-based grouping of nanoparticles for industrial application of safe-by-design

Current practice is that Regulators evaluate the risk from nanoparticles along the whole value chain, from manufacture through application in products to end of life disposal. This project must provide clear input to the evaluation of nanomaterial value chains. Two […]

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ECO24-UFZ: Computer based prediction of the formation of Non-Extractable Residues (NER) of xenobiotics and their metabolites in soils and sediments with regard to their environmental hazard

The project will develop appropriate rules to identify structural alerts. The formation of biogenic NER4 will also be considered within this project. If suitable data are identified from the literature, then the key parameters affecting NER formation will be used […]

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ECO25-ALTER: Development of Soup Tests for the Risk assessment of NER in Soil

In order to fully test the NER for its potential ecotoxicity, an evaluation of extracted residues will also be performed. Currently there are no standard methods, except for isolation and testing of each transformation product. An approach that tests the […]

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S3-UCRAIN: Development of a robust participatory regulatory framework to enhance the wider acceptance of innovative chemical technologies

This project is looking to identify the type and form of policy evidence required by policy makers to operationalize benefit-risk approaches to technology innovation. The project's objectives are to: 1. Map current gaps in existing approaches to developing scientific evidence […]

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ECO23-VUAM: Time-Integrative Passive sampling combined with Toxicity Profiling (TIPTOP): an effect-based strategy for cost-effective chemical water quality assessment

The TIPTOP study will test the following two hypotheses: Compound-by-compound chemical water quality assessment based on concentrations of target-analyzed pollutants is toxicologically and ecologically less relevant and thereby less protective than risk assessment based on bioassay responses to the complex […]

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B12-ETHZ: Assessing the relevance of the dust contribution in consumer exposure to substances from consumer products and articles (DustEx)

This project investigates the importance of house dust as a source of human exposure to substances in consumer products and articles. The project will explore the dust pathway in relation to the direct pathways and develop a decision tree as well as […]

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B13-UCIN: Development of a mechanistic in silico multi-scale framework to assess dermal absorption of chemicals

The research project will build upon existing technology for estimating dermal penetration of chemicals by addressing unmet needs in a mechanistically-based manner that will not only provide an improved risk assessment tool for the immediate future but also enrich the […]

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B11-CERTH: Integrated External and Internal Exposure Modelling Platform (INTEGRA)

The objective of INTEGRA is to bring together all available information within a coherent methodological framework for assessing the source-to-dose continuum for the entire life cycle of substances covering an extensive chemical space. Hence, the major component of INTEGRA will […]

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