Cefic-lri Programme | European Chemical Industry Council

Projects

EMSG42: Increase of the robustness of the fish endocrine assay and avoidance of irrelevant endpoints

The objective of this study was to determine the influence of the test items potassium permanganate, 2-methoxyethanol and octanol to reproduction and the endocrine system of fathead minnow (Pimephales promelas). For this purpose, mature male and female fathead minnow were exposed in […]

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21DAY: Phase 3 of the validation of the OECD Fish Screening Assay

The eight studies in the attached report were conducted as part of OECD Test Guideline program to validate a standardized OECD protocol for a 21-day fish screening assay for the detection of endocrine active substances (i.e. estrogen, aromatase inhibitors, androgen). […]

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D2.2-VITO: Generation and Application of a Model to Determine Intra- and Inter-individual Variation in Biomarkers

Biomarkers which reflect levels of pollutants in the human body offer a unique opportunity to investigate impact of environmental pollution on humans. Biomarker levels in the general population are influenced by genetic, physiological and external factors. Knowledge on which factors […]

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A2.5-TNO: Evaluation of Real and Theoretical Effectiveness of Skin Protection Equipment

The aim of the project was to analyse the parameters of dermal exposure and protection which are most relevant for human health; the quality of data from today's practice of exposure monitoring and PPE testing; the existing knowledge and gaps […]

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A1.3-IOM: Establish the Framework and Operating system for a Cefic Database (CEMAS)

The CEMAS (Cefic Exposure MAnagement System) research project has led to the development of a workplace chemicals exposure and risk evaluation tool that facilitates the delivery of solutions specific to sector groups, including targeted advice from sectors on assessing and […]

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ECO4-RIVO: MonitoringBase. Collation and Evaluation of Monitoring Programmes and Measured Environmental Concentration Data on Organic Chemicals in European Aquatic Environments

To facilitate retrieval of background concentrations and ranges of organic chemical concentrations in the marine and freshwater environment as input for various LRI models (e.g. multi-media, estuary models), ”MonitoringBase” was developed. This database includes information, references and links to more […]

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ECO3B-DELFT: Generic Estuary Modelling System to Evaluate Transport, Fate and Impact of Contaminants (GEMCO)

European estuarine and coastal waters may contain a range of organic and inorganic contaminants. Reliable methods are needed to assess how these behave in the three marine environmental compartments: offshore, estuarine and coastal zones. Transport and fate of contaminants in […]

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EEM3-UDUR: Terrestrial Runoff Modeling for Risk Assessment of Chemical Exposure (TERRACE)

This project aims to create an integrated software package to assess the transport of chemical pollutants in the environment. It will provide European and national regulatory agencies and industry with a state-of-the-art tool for better prediction of concentrations of chemicals […]

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CC2-MRCT: Gene Expression Profiling of Skin Carcinogenesis in Mice Using cDNA Microarrays

Skin cancers are very common in humans - with around one million cases/year in the US - and their development can be affected by stimulators of growth such as certain chemicals. Although initiation is clearly extremely important, clonal expansion (promotion) […]

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EEM9-PGEU: Quantitative Structure-Activity Relationships software for data management

The software system will consist of functional modules allowing evaluation of the data stored in a database and various user interface modules. Compounds database will contain chemical structure, identifiers (including CAS numbers), imported descriptors and experimental data. The functional modules […]

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