Cefic-lri Programme | European Chemical Industry Council

Projects

EMSG33: Chemical Repository

OECD Test Guideline Validation: to provide a set of defined test chemicals for the OECD test methods development for endocrine active chemicals and to guarantee that test method validation under OECD leads to reliable results by always using the same […]

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A2.3: International Workshop on Methods to Determine Dermal Permeation for Human Risk Assessment

This Workshop was designed to bring together relevant expertise and to reach a consensus recommendation on a standardised protocol for in vitro determination of permeability coefficients. The proposed protocol is intended, in the first instance, for testing aqueous soluble chemicals […]

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ECO3B-DELFT: Generic Estuary Modelling System to Evaluate Transport, Fate and Impact of Contaminants (GEMCO)

European estuarine and coastal waters may contain a range of organic and inorganic contaminants. Reliable methods are needed to assess how these behave in the three marine environmental compartments: offshore, estuarine and coastal zones. Transport and fate of contaminants in […]

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R2-BIHH: The Physiological and Bronchial Inflammatory Marker Response to Exposure in the Workplace in Patients With Occupational Asthma

Occupational asthma is the commonest occupational lung disease, accounting for 5% of all cases of asthma, and incidence is rising. Sufferers lose on average half their total take-home income (including compensation) for four years after diagnosis. Whilst the clinical and […]

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EEM3-UDUR: Terrestrial Runoff Modeling for Risk Assessment of Chemical Exposure (TERRACE)

This project aims to create an integrated software package to assess the transport of chemical pollutants in the environment. It will provide European and national regulatory agencies and industry with a state-of-the-art tool for better prediction of concentrations of chemicals […]

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B1.1-FRAU: Identification of Structure Activity Relationships Alerts for Substances With Low NOELs (REPDOSE)

The toxicological data profiles of many of the more than 100,000 substances included in the EINECS are incomplete. Scientific tools are needed to minimize test requirements and to prioritise research needs. Here consideration of Structure Activity Relationships (SAR) could be […]

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EEM9-PGEU: Quantitative Structure-Activity Relationships software for data management

The software system will consist of functional modules allowing evaluation of the data stored in a database and various user interface modules. Compounds database will contain chemical structure, identifiers (including CAS numbers), imported descriptors and experimental data. The functional modules […]

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B2.1-TNO: Characterisation of Uncertainty and Variation in Assessment of Chronic Occupational Exposure

Many adverse health effects of chemical exposure occur after repeated contact over long periods. In assessing the risks of such chronic effects in the workplace, "reasonable worst case" estimates of exposure during a shift or working day are often used. […]

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ECO1B-WRCN: Comparison of Marine and Freshwater Data and Test Methods Review of Literature – Phase I

The environmental risk posed by any new chemical produced or used in substantial quantities in the EU had to be assessed. This process involved estimating the concentration of the substance that could be present in water without harming aquatic life. […]

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B2.2-FoBiG: Provide Examples Where Risk Characterisations can be Conducted With the Existing and Possible Inadequate Data Sets

This project will evaluate the estimates used today by several organisations (e.g. U.S.-EPA, WHO, EU) to assess the human health risks of chemical exposure, which result in the derivation of human limit values such as acceptable daily intake, reference doses […]

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