Cefic-lri Programme | European Chemical Industry Council

Projects

EMSG34A: Validation of the OECD protocol for the surgical castrate rat (Hershberger) assay

The objective of this project was the evaluation and validation of the Hershberger assay as part of the official OECD validation of this test method. This test, developed under the EDTA programme, is designed to help detect chemicals interfering with […]

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A1.3-IOM: Establish the Framework and Operating system for a Cefic Database (CEMAS)

The CEMAS (Cefic Exposure MAnagement System) research project has led to the development of a workplace chemicals exposure and risk evaluation tool that facilitates the delivery of solutions specific to sector groups, including targeted advice from sectors on assessing and […]

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EMSG34B: Validation of the OECD Protocol for the Rat Uterotrophic assay

The objective of this project was the evaluation and validation of the uterotrophic assay as part of the official OECD validation of this test method. This uterotrophic bioassay is intended to identify the in vivo activity of compounds that are […]

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CC2-MRCT: Gene Expression Profiling of Skin Carcinogenesis in Mice Using cDNA Microarrays

Skin cancers are very common in humans - with around one million cases/year in the US - and their development can be affected by stimulators of growth such as certain chemicals. Although initiation is clearly extremely important, clonal expansion (promotion) […]

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ECO4-RIVO: MonitoringBase. Collation and Evaluation of Monitoring Programmes and Measured Environmental Concentration Data on Organic Chemicals in European Aquatic Environments

To facilitate retrieval of background concentrations and ranges of organic chemical concentrations in the marine and freshwater environment as input for various LRI models (e.g. multi-media, estuary models), ”MonitoringBase” was developed. This database includes information, references and links to more […]

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EMSG33: Chemical Repository

OECD Test Guideline Validation: to provide a set of defined test chemicals for the OECD test methods development for endocrine active chemicals and to guarantee that test method validation under OECD leads to reliable results by always using the same […]

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A2.3: International Workshop on Methods to Determine Dermal Permeation for Human Risk Assessment

This Workshop was designed to bring together relevant expertise and to reach a consensus recommendation on a standardised protocol for in vitro determination of permeability coefficients. The proposed protocol is intended, in the first instance, for testing aqueous soluble chemicals […]

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ECO3B-DELFT: Generic Estuary Modelling System to Evaluate Transport, Fate and Impact of Contaminants (GEMCO)

European estuarine and coastal waters may contain a range of organic and inorganic contaminants. Reliable methods are needed to assess how these behave in the three marine environmental compartments: offshore, estuarine and coastal zones. Transport and fate of contaminants in […]

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R2-BIHH: The Physiological and Bronchial Inflammatory Marker Response to Exposure in the Workplace in Patients With Occupational Asthma

Occupational asthma is the commonest occupational lung disease, accounting for 5% of all cases of asthma, and incidence is rising. Sufferers lose on average half their total take-home income (including compensation) for four years after diagnosis. Whilst the clinical and […]

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