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B17: SHINE: Target and non-target Screening of cHemicals in the Indoor enviroNment for human Exposure assessment

Principal Investigator

Dr Marja Lamoree

Address:

De Boelelaan 1087, 1081 HV Amsterdam,

The Netherlands

Tel: +31 20 5989573

E-mail: marja.lamoree@vu.nl

 

Collaborators

Dr Katleen De Brouwere, Researcher, VITO (Flemish Institute for Technological Research), Mol, Belgium

Stuart Harrad, Professor, School of Geography, Earth & Environmental Sciences, University of Birmingham, Edgbaston, Birmingham

Prof. Dr Cynthia de Wit, Professor, Department of Environmental Science and Analytical Chemistry (ACES), Stockholm University, Stockholm

Prof. Dr Adrian Covaci, Professor, Toxicological Center, University of Antwerp, Wilrijk, Belgium

Description

The last couple of years have seen substantial efforts expended on the development of sophisticated, high tier modelling of integrated exposure (including via indoor air), such as INTEGRA (developed in a CEFIC LRI project) and Merlin Expo; however these models have not yet been thoroughly tested for a wide range of chemicals, including these new chemicals. As many of them will be more polar or possess other properties than previously investigated (‘classical’) compounds, the existing models also need to be checked for their applicability to these new chemicals.

Objectives

The following objectives have been set for this project:

  1. To provide an overview of existing information on chemicals found indoors by carrying out a literature search. This review will be mainly based on the ECHA chemicals database, results of ongoing and previous LRI projects, and peer reviewed literature.
  2. To carry out sampling and targeted analysis of emerging contaminants in dust and air of schools/daycare centers, homes and offices in various European countries.
  3. To conduct non-target screening of the same samples collected under objective 2 to identify additional contaminants and combinations of chemicals.
  4. To verify if existing exposure models can be used for the new chemicals found, and propose modifications to the models if needed.
  5. To compare the measured and modelled data with biomonitoring data from the literature and other projects in which partners are participating.

Timeline: May 2016 > May 2019

LRI funding: € 305.323

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