Cefic-lri Programme | European Chemical Industry Council

B17: SHINE: Target and non-target Screening of cHemicals in the Indoor enviroNment for human Exposure assessment

Principal Investigator

Dr Marja Lamoree
De Boelelaan 1087
1081 HV
Amsterdam
The Netherlands
marja.lamoree@vu.nl
Tel. +31 20 5989573

Collaborators

Dr Katleen De Brouwere, Researcher, VITO (Flemish Institute for Technological Research), Mol, BE
Stuart Harrad, Professor, School of Geography, Earth & Environmental Sciences, University of Birmingham, Edgbaston, UK
Prof. Dr Cynthia de Wit, Professor, Department of Environmental Science and Analytical Chemistry (ACES), Stockholm University, Stockholm, SE
Prof. Dr Adrian Covaci, Professor, Toxicological Center, University of Antwerp, Wilrijk, BE

Description

The last couple of years have seen substantial efforts expended on the development of sophisticated, high tier modelling of integrated exposure (including via indoor air), such as INTEGRA (developed in a CEFIC LRI project) and Merlin Expo; however these models have not yet been thoroughly tested for a wide range of chemicals, including these new chemicals. As many of them will be more polar or possess other properties than previously investigated (‘classical’) compounds, the existing models also need to be checked for their applicability to these new chemicals.

Objectives

The following objectives have been set for this project:

  1. To provide an overview of existing information on chemicals found indoors by carrying out a literature search. This review will be mainly based on the ECHA chemicals database, results of ongoing and previous LRI projects, and peer reviewed literature.
  2. To carry out sampling and targeted analysis of emerging contaminants in dust and air of schools/daycare centers, homes and offices in various European countries.
  3. To conduct non-target screening of the same samples collected under objective 2 to identify additional contaminants and combinations of chemicals.
  4. To verify if existing exposure models can be used for the new chemicals found, and propose modifications to the models if needed.
  5. To compare the measured and modelled data with biomonitoring data from the literature and other projects in which partners are participating.

Related Publications

Publications:

Lucattini L, Poma G, Covaci A, de Boer J, Lamoree MH, Leonards PEG. A review of semi-volatile organic compounds (SVOCs) in the indoor environment: occurrence in consumer products, indoor air and dust. Chemosphere. 2018 Jun;201:466-482.

Posters:

Christina Christia, Giulia Poma, Stuart Harrad, Cynthia de Wit, Pim Leonards, Marja Lamoree, Adrian Covaci. Occurrence of legacy and current-use plasticizers in indoor dust from various EU countries. Chemistry Conference for Young Scientists, February 2018, Blankenberge, Belgium.

Christina Christia, Giulia Poma, Stuart Harrad, Cynthia de Wit, Pim Leonards, Marja Lamoree, Adrian Covaci. Occurrence of legacy and current-use plasticizers in indoor dust from various EU countries. 38th International Symposium on Halogenated Persistent Organic Pollutants, August 2018, Krakow, Poland.

Marja Lamoree, Katleen De Brouwere, Stuart Harrad, Cynthia de Wit, Adrian Covaci, Pim Leonards, Jacob de Boer. Target and non-target screening of chemicals in the indoor environment for human exposure assessment: SHINE. SETAC Europe 27th Annual Meeting, May 2017, Brussels, Belgium.

Marja Lamoree, Katleen De Brouwere, Stuart Harrad, Cynthia de Wit, Adrian Covaci, Pim Leonards, Jacob de Boer. Target and non-target screening of chemicals in the indoor environment for human exposure assessment: SHINE. CEFIC-LRI 19th Annual Workshop, November 2017, Brussels, Belgium.

Marja Lamoree, Katleen De Brouwere, Stuart Harrad, Cynthia de Wit, Adrian Covaci, Pim Leonards, Jacob de Boer. Target and non-target screening of chemicals in the indoor environment for human exposure assessment: SHINE. 26th Annual Meeting of the International Society of Exposure Science (ISES), October 2016, Utrecht, The Netherlands.

Timeline: May 2016 > May 2019

LRI funding: € 305 323

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