Cefic-lri Programme | European Chemical Industry Council

ECO11.3 – Proposal for a ring-test to revise the marine biodegradation screening test

Principal Investigator

Dr Russell Davenport
Newcastle University
School of Civil Engineering and Geosciences
Cassie Building
Newcastle University
Newcastle-upon-Tyne
NE1 7RU
United Kingdom
russell.davenport@newcastle.ac.uk
Tel. +44 191 208 5544

Collaborators

Graham Whale, Shell, UK
Bob Rowles, CEFAS, UK
Jason Snape, AstraZeneca, UK

Description

This project emanates from a previous Cefic-LRI ECO11 funded project entitled “Towards rationally designed hazard, risk and persistency assessment: putting the “bio” back into biodegradability tests” following a call to investigate the influence of microbial biomass and diversity on biotransformation. The aim was to look at the sources of uncertainty in biodegradability tests in order to devise more reliable tests. The success of the project resulted in an invitation to host a “Workshop on the improvement of the OECD 306 screening test”. There was a consensus by the attending regulators and industry that the same principles could be used to revise the current marine biodegradation screening test through an international ring-test. This proposal was produced at the request of the organising committee of the above workshop and Cefic-LRI.

The aim is to devise guidelines and co-ordinate an international ring-test conducted by contract research organisations (CROs) in North America, Japan and Europe, and subsequently collect and analyse the data it produces.

Timeline: September 2016 > June 2017

LRI funding: £ 146 709

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