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EMSG20: Environmental Factors and Male Reproductive Functions. A Cohort Study of the Incidence of Cryptorchidism and Hypospadia in 5000 Newborn Boys in the Rotterdam Area

Principal Investigator

Dr. Rob Weber
Department of Andrology
Academic Hospital Dijkzigt
Dr. Molewaterplein 40
3015 GD Rotterdam
The Netherlands
weber@inw3.azr.nl
Tel: +32 2 650 43 33
Fax: +32 2 650 43 24

Description

This is a study of 10,000 men, their (pregnant) partners and their new-born children. Information will be collected on the incidence of urogenital disorders such as Cryptorchidism, Hypospadia, lifestyle, working conditions of the male partner and time to pregnancy. The quality of paternal semen will also be assessed. 

Related Publications

FH Pierik, A Burdorf, JA Deddens, RE Juttmann, RFA Weber, Maternal and Paternal Risk Factors for Cryptorchidism and Hypospadias: A Case-Control Study in Newborn Boys, Environmental Health Perspectives 2004, 112, 1570-1576.

FH Pierik, A Burdof, JMR Nijman, SMPF de Muinek Keizer-Schrama, RE Juttman, RFA Weber, A high hypospadias rate in The Netherlands, Human Reproduction 2002, 17, 1112-1115.

RFA Weber, FH Pierik, GR Dohle, A Burdorf, Environmental influences on male reproduction, BJU International 2002, 89, 143-148.

Pierik FH, Burdorf A, de Muinck Keizer-Schrama SMPF, Wolffenbuttel KP, Nijman JMR, Juttmann RE, Weber RFA. The cryptorchidism rate in the general population in the Netherlands. Int J Androl 2005 (in press)

Frank H. Pierik FH, James A. Deddens JA, Burdorf A, de Muinck Keizer-Schrama SM, de Jong FH, Weber RFA. The hypothalamus-pituitary-testis axis in boys younger than 6 months: a comparison of cases with cryptorchidism or hypospadias versus controls. Submitted

 

LRI funding: €611,200

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