Cefic-lri Programme | European Chemical Industry Council

Projects

R2-TNO: The Role of Irritancy and Irritant-Induced Inflammation in the Elicitation of Respiratory Hypersensitivity Reactions

A range of low molecular weight chemicals can cause adverse reactions in the airways such as allergic asthma, including occupational asthma. Allergies involve a generally symptom-free induction phase where sensitisation is induced, and an elicitation (challenge) phase, where inhalation of […]

Read more

IA4.6: A Rat IGE Test for the Identification of Chemical Respiratory Allergens

Some chemicals can induce allergies, including allergy of the lungs and other parts of the respiratory tract. (Examples include acid anhydrides, certain diisocyanates, some platinum salts, certain reactive dyes and plicatic acid). This is an important occupational health problem because […]

Read more

D1.1-NOFE: Biomarkers of Exposure – Trends and Key Developments

The aim of the study was to evaluate existing biomarkers of exposure to xenobiotics and analytical methods from the point of view of the possibility of practical use for assessing and managing occupational and environmental health risk. The study encompassed […]

Read more

C1.6: Possibilities and capabilities of 3D-body-scanning systems for the purpose of risk assessment.

The result of this study shows that a vast pool of data is available from the many kinds of measurement surveys that have been carried out using 3D body scanner technology. However, to evaluate the data or to derive the […]

Read more

A2.3: International Workshop on Methods to Determine Dermal Permeation for Human Risk Assessment

This Workshop was designed to bring together relevant expertise and to reach a consensus recommendation on a standardised protocol for in vitro determination of permeability coefficients. The proposed protocol is intended, in the first instance, for testing aqueous soluble chemicals […]

Read more

D2.1-MRCI: Background Incidence of Key Biomarkers of Chemical Exposure within the General Population

The science of biomarkers and measurement of exposures via biomarkers has progressed substantially in the past ten years, resulting in several occupational exposure limits being set on the basis of biomarker measurement, and the acceptance of biomarkers as measurement of […]

Read more

D1.1-SYNG: Study of the Role and Application of Biomarkers in the Management of the Health Risks Associated with Occupational Exposures to Chemicals

The objective of this project was to provide a concise and impartial view of the major developments in academic, institutional and industrial laboratories in Europe, USA and elsewhere working on biomarkers for monitoring human exposure to chemicals. The research into […]

Read more

C1.5: European Sourcebook of Information Describing Human Exposures to Chemicals in the Environment (ExpoFacts)

European exposure factor data have been collected in one centrally available, freely accessible site on the Internet: the ExpoFacts database. The process of compiling the database required locating the exposure factor data and evaluating its general applicability and public availability. […]

Read more

C1.3: Establish a Database of a Number of Parameters Sufficient Relevant for Reliable Prediction of European Consumer Exposures

Many chemicals are used daily in the home, in diverse end-uses such as cleaning, renovating and caring for houseplants. Product labels give advice on safe use, but there is scope to improve understanding of potential risks. One approach is to […]

Read more

A3.3: The EXPOLIS-Index Study, Human Exposure Patterns for Health Risk Assessment:Indoor Determinants of Personal Exposures in the European Expolis Population in Athens, Basel, Grenoble, Milan, Helsinki, Oxford And Praha

Exposure assessment plays a key role in the risk assessment procedure. In order to quantify the associated risk and health impact of a possible pollutant, it is necessary to obtain a description of the full-range of exposure distribution. This project […]

Read more

Cefic-Lri Programme Responsible Care

© Copyright 2017 Cefic | European Chemical Industry Council. All rights reserved | Terms and Conditions of Use