Cefic-lri Programme | European Chemical Industry Council

Projects

AIMT4-UM: DECO2: Moving from DECO towards OECD

The aim of this project is to establish a framework for tools usable in integrated approaches. For this, efforts in our previous DECO project (CEFIC-LRI AIMT3 grant) will be advanced. DECO focused on the prediction of in vivo repeated dose […]

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C3-ED: A comprehensive Epigenomic profile of liver tissue from Rat and Mouse

This project will apply a comprehensive strategy to characterise and curate genome wide methylomes in liver tissues from rats and mouse. This will involve correlation of the profiles generated with public data sets for RNA expression (transcriptomics) and histone modification profiles […]

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B15-UCRAN: Developing a robust method of allocating efficiency measures to regulatory instruments in the chemicals industry

This project aims to improve the depth and availability of knowledge and understanding of the specific factors affecting the efficiency of risk management measure (RMM) to control human (worker and consumer) and environmental exposures that may result from the use […]

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N4-WAG: Science-based grouping of nanoparticles for industrial application of safe-by-design

Current practice is that Regulators evaluate the risk from nanoparticles along the whole value chain, from manufacture through application in products to end of life disposal. This project must provide clear input to the evaluation of nanomaterial value chains. Two […]

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EMSG58-MNEGRI: Human adverse health effects of endocrine active substances: assessment of the quality of individual epidemiological studies and of the overall mechanistic and epidemiologic evidence

The project's objective is to develop a systematic evaluation scheme to assess the quality and reliability of the epidemiological evidence for endocrine active substances to exert adverse effects based on an endocrine mode of action. This scheme is then to […]

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S3-UCRAIN: Development of a robust participatory regulatory framework to enhance the wider acceptance of innovative chemical technologies

This project is looking to identify the type and form of policy evidence required by policy makers to operationalize benefit-risk approaches to technology innovation. The project's objectives are to: 1. Map current gaps in existing approaches to developing scientific evidence […]

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ECO25-ALTER: Development of Soup Tests for the Risk assessment of NER in Soil

In order to fully test the NER for its potential ecotoxicity, an evaluation of extracted residues will also be performed. Currently there are no standard methods, except for isolation and testing of each transformation product. An approach that tests the […]

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ECO24-UFZ: Computer based prediction of the formation of Non-Extractable Residues (NER) of xenobiotics and their metabolites in soils and sediments with regard to their environmental hazard

The project will develop appropriate rules to identify structural alerts. The formation of biogenic NER4 will also be considered within this project. If suitable data are identified from the literature, then the key parameters affecting NER formation will be used […]

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ECO23-VUAM: Time-Integrative Passive sampling combined with Toxicity Profiling (TIPTOP): an effect-based strategy for cost-effective chemical water quality assessment

The TIPTOP study will test the following two hypotheses: Compound-by-compound chemical water quality assessment based on concentrations of target-analyzed pollutants is toxicologically and ecologically less relevant and thereby less protective than risk assessment based on bioassay responses to the complex […]

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S2-IOM: Foresight study on introduction of new technologies; the case of nanotechnology

The primary objective of this project is to identify the drivers of effective policy in the area of strategic development of novel technologies. Specific objectives include the following: 1.  To strengthen the link between technical expressions of risk resulting from […]

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