Cefic-lri Programme | European Chemical Industry Council

Persistence, Bioaccumulation and Toxicity

ECO24-UFZ: Computer based prediction of the formation of Non-Extractable Residues (NER) of xenobiotics and their metabolites in soils and sediments with regard to their environmental hazard

The project will develop appropriate rules to identify structural alerts. The formation of biogenic NER4 will also be considered within this project. If suitable data are identified from the literature, then the key parameters affecting NER formation will be used […]

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ECO25-ALTER: Development of Soup Tests for the Risk assessment of NER in Soil

In order to fully test the NER for its potential ecotoxicity, an evaluation of extracted residues will also be performed. Currently there are no standard methods, except for isolation and testing of each transformation product. An approach that tests the […]

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ECO3A.3-USTO: Evaluation of the predictability and reversibility of environmental accumulation for substances for POP/PBT-like properties

The objectives of these project are: - to gain a quantitative understanding of how chemical and environmental characteristics interact to control long-term time trends of POP/PBT-like substances in various environmental compartments. - to test the ability of current dynamic multimedia models to […]

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ECO9-VUA: Relationships between BCF, BMF and BAF: Improving forecasting of residues in biota in the environment based on laboratory testing

Objectives Overview   Identify the key properties and parameters impacting bioconcentration factor (BCF) measurements in the laboratory and those impacting field bioaccumulation factor (BAF) assessments. Select a test set of chemicals which include high production volume (HPV) substances in the […]

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ECO6-CSL: Identifying Transgeneric Biotransformational Potential

When aquatic organisms are exposed to chemicals in the environment, some of these chemicals maybe universally metabolised, whilst others are either metabolised by specific species/taxa or are non-metabolisable and therefore may bioaccumulate. The objective of this work was to develop […]

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ECO1A-INIA: Relationships Between Persistence, Bioaccumulation Potential and Effects in Waters, Sediments and Soils

Emissions of man-made chemicals can potentially have an adverse impact on the ecological balance in marine and terrestrial environments. Risk assessments have historically considered the potential for bioaccumulation (transference form the environmental compartment to the organisms) but not the potential […]

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ECO1B-WRCN: Comparison of Marine and Freshwater Data and Test Methods Review of Literature – Phase I

The environmental risk posed by any new chemical produced or used in substantial quantities in the EU had to be assessed. This process involved estimating the concentration of the substance that could be present in water without harming aquatic life. […]

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ECO2A-ASTRA: Understanding and Measurement of Persistence in the Marine and Terrestrial Compartments

The persistence of a chemical in the environment - how resistant it is to being broken down in nature - is hard to predict. Its tendency to build up in living organisms - to bioconcentrate or bioaccumulate - is similarly […]

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ECO3A-UTO: Evaluating Multi-Media Fate and Transport models on a Regional and Global Scale

Computer models are increasingly used to simulate the behaviour of chemicals in the environment. Based on data on a chemical's properties, release rates and environmental characteristics, these programmes - known as multimedia fate and transport models (MFTM) predict concentrations in […]

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