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EMSG23: Endocrine Modulating Effects in Fish Along the Elbe River and in Reference Areas. Assessment of Risks Related to the Habitat Conditions and the Natural Variability of Endocrine Functions

Principal Investigator

Dr. Ludwig Karbe
Universität Hamburg
Edmund-Siemers-Allee 1
D – 20146 Hamburg
karbe@uni-hamburg.de
Tel: +49 40 42838 6660
Fax: +49 40 42838 6696

Collaborators

Prof. John Sumpter – Brunel University
john.sumpter@brunel.ac.uk

Description

The aim of the study is to identify effects caused by endocrine modulation in fish and evaluate these with respect to dysfunction in sex differentiation, development of functional organs as well as fecundity. Another aspect is the determination of the variability of these endpoints, including their seasonality. Finally, the impact of effects, if they exist, will be investigated on a population level.

Related Publications

M Hecker, CR Tyler, M Hoffman, S Maddix, L Karbe, Plasma biomarkers in fish provide evidence for endocrine modulation in the Elbe River, Germany, Environmental Science and Technology 2002, 36, 2311-231.

M Hecker, Natural variability of endocrine functions and their modulation by anthropogenic influences, PhD Thesis, University of Hamburg, 2001.

LRI funding: €258,500 (Co-sponsored by the German Federal Government)

Cefic-Lri Programme Responsible Care

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