Intelligent testing
B27- Incorporation of dermal exposure assessment in the Advanced REACH Tool: dART
In 2018 the dermal Advanced REACH Tool (dART) was developed, calibrated and published (Goede 2018, McNally 2019), initiated by the Health and Safety Executive (UK) and the Dutch Ministry of Social Affairs and Employment. The dART has been developed as an extension to the ART model and involves a new mechanistic Tier 2 exposure model for estimating dermal […]
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LRI ECO70: Expanding the applicability domain of the OECD test guideline 309 for biodegradation simulation testing to address difficult-to-test properties
Simulation tests in surface water, soil, and aquatic sediment systems are considered higher tier tests in regulatory persistence assessments. They investigate biodegradation under more realistic environmental conditions, such as the use of natural inocula and lower test substance concentrations, and can generate compartment-specific biodegradation […]
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ECO64: POLY-DEG-SOLve – Applicability and improvements of OECD (bio)degradation testing for water-soluble polymers
In order to tackle the scientific gaps, the research project has the following objectives: -The identification, selection and 14C-synthesis of water-soluble polymers that are representative for polymers applied in consumer and daily care products with different chemistries and biodegradation profiles […]
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ECO62: STREAM – Substance Testing for River-bank filtration And Mobility
The overall aim of this project is to explore an experimental strategy for the assessment of the relevance of River Bank Filtration (RBF) for Persistence, Mobility, and Toxicity (PMT) substances. A laboratory test will be developed to provide reliable data […]
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B24 – Modeling exposure and biodistribution of microplastic particles in the human body
Aim of this project is to develop a human exposure probabilistic modelling framework for microplastics, and to collect input data for scenario analyses and validation. The framework will be flexible so as to enable implementation of updates as key processes […]
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ECO61: HERA-MP – Establishment of a Holistic Environmental Risk Assessment for MicroPlastics in the terrestrial environment using the study of environmentally relevant particles
The objective of this proposal is to apply a number of OECD/ISO standardized effect test systems on several different types of MPs (WP2), including environmentally relevant MP as well as on a subset of different types of MPs of specific […]
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ECO59 : FRAGMENT-MNP: Developing a mechanistic model of Micro and NanoPlastic FRAGMentation in the ENvironmenT
The overarching objective of this project is to develop and deliver a pragmatic open-source mechanistic model of how environmental factors affect plastic fragmentation and degradation rates. The model will be applicable across a range of conditions in multiple environmental compartments. […]
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ECO58 : Comprehensive additive release and bioaccessibility model for risk assessment of micro- and nano-plastics in the environment
The ubiquitous occurrence of plastics in natural waters1, 2 is a consequence of vast and increasing utilization of synthetic polymers in commercial, industrial, and consumer applications. While the implications of continuous ecological exposure to plastic particles in the nano- to […]
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ECO57 : μPLANET – microPlastic Long-range transport Assessment aNd Estimation Tools
Recent research has highlighted the apparent ubiquity of plastic debris, including Microplastic Particles (MPs), across the planet and particularly in the oceans. The release of MPs to the environment represents a particular concern given their resistance to degradation. The continuous […]
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ECO56: UTOPIA: Development of a mUltimedia uniT world OPen-source model for mIcroplAstic
The main objective of UTOPIA is to develop an open-source unit world multimedia modeling platform to synthesize knowledge and understanding about the fate of microplastic in the environment. The UTOPIA project aims to deliver a general purpose open-source modeling platform […]
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