Projects
ANP2: Interlaboratory comparison of PFAS Analytics in water samples
With different legislations including or aiming to include limits for either specific or sets of PFAS, it is needed to accurately and precisely confirm their absence/ presence in aqueous environments. A set of ‘official’ methods are available, albeit often accompanied by some uncertainties on their […]
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B27- Incorporation of dermal exposure assessment in the Advanced REACH Tool: dART
In 2018 the dermal Advanced REACH Tool (dART) was developed, calibrated and published (Goede 2018, McNally 2019), initiated by the Health and Safety Executive (UK) and the Dutch Ministry of Social Affairs and Employment. The dART has been developed as an extension to the ART model and involves a new mechanistic Tier 2 exposure model for estimating dermal […]
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LRI ECO70: Expanding the applicability domain of the OECD test guideline 309 for biodegradation simulation testing to address difficult-to-test properties
Simulation tests in surface water, soil, and aquatic sediment systems are considered higher tier tests in regulatory persistence assessments. They investigate biodegradation under more realistic environmental conditions, such as the use of natural inocula and lower test substance concentrations, and can generate compartment-specific biodegradation […]
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ECO63: Comprehensive mechanistic assessment of sorption of chemically diverse water-soluble and dispersible polymers to mineral and organic surfaces in soils, sediments and sludge – from fundamentals to implications
The first comprehensive assessment of adsorption and desorption characteristics of water soluble polymers (WSPs) and water dispersible polymers (WDPs) to mineral surfaces for environmental fate assessment was recently published by the group of the principal investigator (Sanders et. al) . […]
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ECO67: Plastic article fragmentation in soils and marine environments (FRAGMENT-ARTICLE)
The FRAGMENT-ARTICLE project will identify key formulation factors that impact the degradation and fragmentation into micro- and nanoplastics of post-use plastic articles in the environment. It will build a quality dataset on the influence of product formulation, use this to […]
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AIMT12: NGRA uncertainty assessment: iterating a conceptual model through increasingly complex case studies and comparison to in vivo-based assessments
The overarching goal is to test the hypothesis that in some situations new approach method (NAM)-based assessments bear less uncertainty whereas in others, animal-data based assessments will have less uncertainty. To achieve such, the specific project objectives include: Performing probabilistic […]
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ECO68 Integration of research results from the ECO56-60 microplastics project cluster
The project will deliver a new version of UTOPIA that will integrate state-of-the-science knowledge about the behavior of microplastic in the environment and support calculation of exposure metrics and representative concentrations of microplastic to support risk assessment.
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ECO65: Characterizing the uncertainty in MAF values for aquatic receptors estimated using the KEMI MAF
We propose a project to publish a paper that more fully explores the uncertainty and variation in MAF values for mixtures that occur in surface waters. The objectives of the second paper are to clearly describe the biases in the […]
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ECO66: ENCORE – ENvironmental CO-exposure and Risk Estimation
The general objective of this project proposal is therefore to develop a probabilistic modelling framework that allows to identify the priority chemicals for co-exposure risk at the watershed level. The environmental fate model at the core of this probabilistic framework […]
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B26: DERM – Dermal Exposure, a Review of current knowledge on the uptake of Micro-and nano-plastics
This research project aims to investigate the current understanding of the risk of dermal uptake of MNPs. Information on the impact of particle size, shape (spherical, needle, irregular, fibre), polymer composition, hydrophobicity, charge, surface chemistry and aging will be investigated […]
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