Projects
EMSG31: Aquatic Invertebrates Study – Aquatic Toxicity Project C
Evaluate the published information on the reproductive endocrinology of aquatic invertebrates with a view to evaluate their potential use in aquatic hazard identification of endocrine modulators.
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EMSG13: Genetic Sex Determination of Fish – Aquatic Toxicity Project D
Conduct a literature review on present understanding of sex determination mechanisms in wildlife and the current use of markers of genetic sex for wildlife species selected for use in the testing and evaluation of effects of endocrine modulators. This knowledge […]
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EMSG34A: Validation of the OECD protocol for the surgical castrate rat (Hershberger) assay
The objective of this project was the evaluation and validation of the Hershberger assay as part of the official OECD validation of this test method. This test, developed under the EDTA programme, is designed to help detect chemicals interfering with […]
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EMSG34B: Validation of the OECD Protocol for the Rat Uterotrophic assay
The objective of this project was the evaluation and validation of the uterotrophic assay as part of the official OECD validation of this test method. This uterotrophic bioassay is intended to identify the in vivo activity of compounds that are […]
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EMSG35-BASF: Enhanced OECD TG 407 – Development and Validation
Concerns that toxicological test guidelines may not optimally detect effects on the endocrine system have lead to proposals to enhance the current sub-acute rodent OECD Test Guideline No. 407 (OECD 1995). The efficacy of the modified enhanced (phase 2) protocol […]
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EMSG33: Chemical Repository
OECD Test Guideline Validation: to provide a set of defined test chemicals for the OECD test methods development for endocrine active chemicals and to guarantee that test method validation under OECD leads to reliable results by always using the same […]
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