Principal Investigator
Prof. Dr. Henk Goos
University of Utrecht
Collaborators
Prof. John Sumpter, Brunel University
Description
The aim of the study was to study neuro-endocrine regulation, particularly the brain-pituitary-gonad (BPG) axis, 3 freshwater fish species (catfish, trout and tilapia) exposed to 4-nonyl phenol (4-NP) or oestradiol (EE). The research also sought to establish an immortalised gonadotroph cell line for use in in vitro studies. The research was conducted in 3 laboratories – at the University of Brunel, University of Utrecht and University of Tel Aviv – and organised via the University of Utrecht.
Related Publications
Publications:
CA Harris, EM Santos, A Janbakhsh, TG Pottinger, CR Tyler, JP Sumpter. Nonylphenol affects gonadotropin levels in the pituitary gland and plasma of female rainbow trout. Environ Sci Technol. 2001 Jul 15;35(14):2909-16.
