Cefic-lri Programme | European Chemical Industry Council

EMSG9: Development of a Sensitive Assay for Androgenic Activity Using Prostate Cells Lines

Principal Investigator

Paul Rumsby PhD
Bibra Toxicology International
Woodmansterne Road Carshalton
GB – SM5 4DS Surrey


The objective of the project is to develop an in vitro assay for androgenic activity based on the use of prostate cell lines. This involves testing and validation of the cell line LNCaP, which is sensitive to weak androgens, anti-androgens, progestrogens and oestrogens. Further to develop a sensitive specific assay for androgenic activity.

Related Publications

Rumsby PC.Development of a sensitive assay for androgenic activity using prostate cell lines. TNO BIBRA : Final Report No. 3306, May 2000.

LRI funding: €54,000

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