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EMSG27: Environmental Effects on Uterine Tissues of Baltic Seals With Special Emphasis on Organochlorines and Uterine Leiomyomas

Principal Investigator

Prof. Mats Olsson
Swedish Natural Museum of History
Contaminant Research Group
PO Box 50007
SE-104 05 Stockholm
Tel: +46 8 5195 4111
Fax: +46 8 5195 4256
mats.olsson@nrm.se

Collaborators

Dr Britt-Marie Bäcklin - Swedish Natural Museum of History
britt-marie.backlin@pharmacia.com
LRI Monitor: Dolf van Wijk - EUROCHLOR
dvw@cefic.be

Description

The study investigated whether leiomyomas in grey seals, collected during the period of decreased levels of organo-chlorines, were in a regressive phase; and whether the period of increased levels of organo-chlorines caused the leiomyomas to proliferate. In addition, in vitro studies were conducted to characterise the growth control mechanism of grey seals leiomyoma cells.

Related Publications

Britt-Marie Backlin, L. Eriksson and M. Olovsson. Histology of uterine leiomyoma and occurrence in relation to reproductive activity in the Baltic grey seal (halichoerus grypus). Veterinary Pathology : accepted for publication

LRI funding: €63,000

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