Biomonitoring is a useful tool to aid the assessment of exposure to many chemical substances but currently our ability to detect hazardous substances (or their metabolites and effects) may often exceed our understanding of the biological relevance of these results. There are well-established frameworks for developing and using BGVs in the occupational health field but these are limited in number (<100) and are only for data-rich substances that have been in use for some time. BGVs for new substances and those with undefined dose-response relationships are difficult to derive and the problems are compounded at environmental levels that are far below doses used in toxicity studies or those encountered in the occupational setting. A variety of approaches have been used, misused or are being developed to utilise biomonitoring data from environmental exposures.
Publications are expected in 2010.