Cefic-lri Programme | European Chemical Industry Council

Complex environments

ECO27-USHE: Chemicals: Assessment of Risks to Ecosystem Services (CARES)

Aim: To facilitate engagement of the chemical industry, academia and regulators to help develop and evaluate the ecosystem service approach in guiding risk assessment schemes for any type of xenobiotic chemical. Objectives: Review and evaluate state of knowledge and available […]

Read more

ECO8.3-NC3Rs-EAWAG: Round-robin test of the RTgill-W1 cell line assay to study its robustness in establishment and inter-laboratory comparability

To accomplish international recognition of the RTgill-W1 cell line assay for predicting acute toxicity to fish, the project aims to initiate a round-robin trial in order to test the robustness of the established methodology. In particular, the team aims to evaluate the […]

Read more

LRI AWARD 2010: In Quest of new fingerprints of exposure to VOC from consumer products

Volatile organic compounds (VOCs) are ubiquitous in indoor air and their origin is a plethora of various emission sources including building related materials, furniture, equipment and consumer and household related products. Currently, there is international recognition of the contribution of […]

Read more

LRI AWARD 2013: Environmental programming of respiratory allergy in childhood: the applicability of saliva to study the effect of environmental exposures on DNA methylation

Environmental exposures during fetal and early life may contribute to complex disease later in life such as allergic diseases (AD), neurodegenerative diseases and cancer. The underlying mechanisms are still undiscovered, but changes in the epigenetic regulation of gene expression (such […]

Read more

Q3-UMA: Sound Science: Selective citation in science based decision-making

The European Chemical Industry Council has provided funding to Maastricht University for a research project on Research Integrity by exploring one of the most suspected contributors to questionable research practices: selective citation. It is generally accepted that scientific papers should […]

Read more

C3-ED: A comprehensive Epigenomic profile of liver tissue from Rat and Mouse

This project will apply a comprehensive strategy to characterise and curate genome wide methylomes in liver tissues from rats and mouse. This will involve correlation of the profiles generated with public data sets for RNA expression (transcriptomics) and histone modification profiles […]

Read more

AIMT4-UM: DECO2: Moving from DECO towards OECD

The aim of this project is to establish a framework for tools usable in integrated approaches. For this, efforts in our previous DECO project (CEFIC-LRI AIMT3 grant) will be advanced. DECO focused on the prediction of in vivo repeated dose […]

Read more

EMSG58-MNEGRI: Human adverse health effects of endocrine active substances: assessment of the quality of individual epidemiological studies and of the overall mechanistic and epidemiologic evidence

The project's objective is to develop a systematic evaluation scheme to assess the quality and reliability of the epidemiological evidence for endocrine active substances to exert adverse effects based on an endocrine mode of action. This scheme is then to […]

Read more

EMSG57-LAKIND: Endocrine disruptors and obesity, diabetes and heart disease: State of the science and biological plausibility

This project builds on (i) the lessons learned from the recently completed work on methodologic issues affecting epidemiologic research on BPA and (ii) the findings of the project (conducted under Cefic-LRI EMSG54) related to the importance of harmonization of epidemiologic methods for […]

Read more

AIMT2-TNO: Mechanism-based characterisation of systemic toxicity for RepDose database substances employing in vitro toxicogenomics

Many in vitro toxicogenomics initatives so far focus on the overlap between in vitro mechanistic responses and in vivo toxicity, but are primarily concerned with mechanistic studies and hazard identification. Purpose of this study is to extend this towards applications of […]

Read more

Cefic-Lri Programme Responsible Care

Terms and Conditions of Use | Privacy Policy | Cookie Policy | Coockie Settings

© Copyright 2017 Cefic | European Chemical Industry Council. All rights reserved.