Projects
B16-TNO: External validation of Tier-1 workers dermal exposure estimates in ECETOC TRA
As indicated in the Invitation to Tender, the objective of the proposed project is to obtain a set of dermal exposure estimates aligned with PROCs suitable for Tier-1 chemical safety estimates. According to the tender document, the worker dermal exposure […]
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R2-BIHH: The Physiological and Bronchial Inflammatory Marker Response to Exposure in the Workplace in Patients With Occupational Asthma
Occupational asthma is the commonest occupational lung disease, accounting for 5% of all cases of asthma, and incidence is rising. Sufferers lose on average half their total take-home income (including compensation) for four years after diagnosis. Whilst the clinical and […]
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B2.1-TNO: Characterisation of Uncertainty and Variation in Assessment of Chronic Occupational Exposure
Many adverse health effects of chemical exposure occur after repeated contact over long periods. In assessing the risks of such chronic effects in the workplace, "reasonable worst case" estimates of exposure during a shift or working day are often used. […]
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A1.2-UNAB: Database Of European Workplace Exposure Research Activities (HEROX)
Cefic identified a need for an inventory of European research on human workplace exposure to chemicals. Access to this information is needed for setting safe occupational exposure limits and to help quantify economic and health implications of exposures. A database […]
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A1.3-UNAB: Development Of A Database For Workplace Exposure Measurements
Measurement of human exposure at work forms the cornerstone of risk management strategies. With the advent of powerful computer databases these measurements have been collected in several parts of Europe, by industry, government agencies and others such as universities and […]
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A2.1: Literature Survey On Dermal Deposition In The Chemical Industry
Making reliable estimates of the amounts of chemicals deposited on the skin and clothing in the workplace is essential in evaluating any health risks. It also helps in assessing the effectiveness of protective equipment. There is a lack of detailed […]
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A2.2-UNJM: Determination of the Optimal Physico-Chemical Parameters to Use in a QSAR Approach to Predict Skin Permeation Rate
Many toxic chemicals can enter the body via the skin. Measuring a chemical's ability to cross the skin is difficult, time-consuming and costly. One solution is to develop models relating skin permeability to chemical structure - known as a quantitative […]
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A2.5-TNO: Evaluation of Real and Theoretical Effectiveness of Skin Protection Equipment
The aim of the project was to analyse the parameters of dermal exposure and protection which are most relevant for human health; the quality of data from today's practice of exposure monitoring and PPE testing; the existing knowledge and gaps […]
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IRTA2-002-UUIR: Heterogeneity in Response to Iso-Cyanate Exposure in the Work Environment
Di-isocyanates are in many countries a major cause of occupational asthma. However, few recent studies are available in which exposure to isocyanates has been measured and related to respiratory disease risk. Thus, information about exposure response relationships is extremely limited. […]
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A1.3-IOM: Establish the Framework and Operating system for a Cefic Database (CEMAS)
The CEMAS (Cefic Exposure MAnagement System) research project has led to the development of a workplace chemicals exposure and risk evaluation tool that facilitates the delivery of solutions specific to sector groups, including targeted advice from sectors on assessing and […]
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