Cefic-lri Programme | European Chemical Industry Council

Projects

ECO14-USTO: Development and validation of an abbreviated in vivo fish bioconcentration test

The overall objective of the research project is to reduce the cost and the number of animals needed to measure the bioconcentration factor (BCF) of organic chemicals in fish, using the accepted ”gold standard” OECD 305 as the point of reference. […]

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ECO12: Validation Chemicals for Assessing Biodegradation Tests

This project aims to develop a list of reference chemicals covering a range of environmental persistence and non-persistence. This reference set would be available for use to validate modifications to existing biodegradation test methods and to develop new test methods. […]

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EEM2: Validation of the Risk Assessment Module Against Observations and Against Other Models in the Context of EMEP POP Modelling Intercomparison Study

The ADEPT software is a quick assessment tool to calculate European concentrations and deposition of airborne chemical contaminants. In a tiered approach to risk assessment this could be the second or even first tier level. The model gives the result […]

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ECO8: Development of a strategy to predict acute fish lethality using fish cell lines and fish embryos

It is the goal of this research project to investigate if in vitro approaches based on fish cell lines and/or fish embryos can be improved to be widely accepted as an alternative to the acute fish test. With regard to […]

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B3.3: The Intake Fraction (iF) concept: modelling, expansion and application tests

In order to help correlate the exposure of a population to a toxicant directly to the source of exposure, researchers have developed a concept called the intake fraction (iF), which is a dimensionless variable. The estimation of the iF relationship […]

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EMSG42: Increase of the robustness of the fish endocrine assay and avoidance of irrelevant endpoints

The objective of this study was to determine the influence of the test items potassium permanganate, 2-methoxyethanol and octanol to reproduction and the endocrine system of fathead minnow (Pimephales promelas). For this purpose, mature male and female fathead minnow were exposed in […]

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