Projects

Intelligent testing Nanotechnology Testing

N4-WAG: Science-based grouping of nanoparticles for industrial application of safe-by-design

Current practice is that Regulators evaluate the risk from nanoparticles along the whole value chain, from manufacture through application in products to end of life disposal. This project must provide clear input to the evaluation of nanomaterial value chains. Two […]

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Complex environments Human Health Effects

EMSG58-MNEGRI: Human adverse health effects of endocrine active substances: assessment of the quality of individual epidemiological studies and of the overall mechanistic and epidemiologic evidence

The project's objective is to develop a systematic evaluation scheme to assess the quality and reliability of the epidemiological evidence for endocrine active substances to exert adverse effects based on an endocrine mode of action. This scheme is then to […]

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Intelligent testing Bioaccumulation and Toxicity, Persistence

ECO24-UFZ: Computer based prediction of the formation of Non-Extractable Residues (NER) of xenobiotics and their metabolites in soils and sediments with regard to their environmental hazard

The objective of this project is to define alerts from (sub)structures of environmental chemicals to predict the formation of non-extractable residues (NER) and their metabolites in soils and sediments. The intention is to provide a computerized tool to predict whether […]

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Intelligent testing Bioaccumulation and Toxicity, Environment, Persistence

ECO25-ALTER: Development of Soup Tests for the Risk assessment of NER in Soil

In order to fully test the NER for its potential ecotoxicity, an evaluation of extracted residues will also be performed. Currently there are no standard methods, except for isolation and testing of each transformation product. An approach that tests the […]

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Intelligent testing Societal Acceptance

S3-UCRAIN: Development of a robust participatory regulatory framework to enhance the wider acceptance of innovative chemical technologies

This project is looking to identify the type and form of policy evidence required by policy makers to operationalize benefit-risk approaches to technology innovation. The project's objectives are to: 1. Map current gaps in existing approaches to developing scientific evidence […]

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Intelligent testing Testing Strategies and Risk Assessment

ECO23-VUAM: Time-Integrative Passive sampling combined with Toxicity Profiling (TIPTOP): an effect-based strategy for cost-effective chemical water quality assessment

The TIPTOP study will test the following two hypotheses: Compound-by-compound chemical water quality assessment based on concentrations of target-analyzed pollutants is toxicologically and ecologically less relevant and thereby less protective than risk assessment based on bioassay responses to the complex […]

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Acceptance of technology Societal Acceptance

S2-IOM: Foresight study on introduction of new technologies; the case of nanotechnology

The primary objective of this project is to identify the drivers of effective policy in the area of strategic development of novel technologies. Specific objectives include the following: 1.  To strengthen the link between technical expressions of risk resulting from […]

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Intelligent testing Consumer Exposure

B13-UCIN: Development of a mechanistic in silico multi-scale framework to assess dermal absorption of chemicals

The research project will build upon existing technology for estimating dermal penetration of chemicals by addressing unmet needs in a mechanistically-based manner that will not only provide an improved risk assessment tool for the immediate future but also enrich the […]

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Intelligent testing Consumer Exposure

B12-ETHZ: Assessing the relevance of the dust contribution in consumer exposure to substances from consumer products and articles (DustEx)

This project investigates the importance of house dust as a source of human exposure to substances in consumer products and articles. The project will explore the dust pathway in relation to the direct pathways and develop a decision tree as well as […]

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Acceptance of technology Ecosystems Relevance

ECO19-RUG: ChimERA – An integrated modelling tool for ecological risk assessment

The first objective of this project is to couple separate exposure and effect models (here called'sub-models') into a chemical integrated exposure and effect ecosystem model for ecological risk assessment (ChimERA) for the aquatic environment. This will be realized by combining […]

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